Tuesday September 16th
| Phaedon Institute SenoTherapeutics Summit | |
| 08.30 - 09.15 | Registration |
| 09.15 - 09.25 | Welcome note |
| 09.25 - 12.25 | Session 1: New discoveries, biomarkers and clinical trials: a perspective from academics |
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9:25-9:50 James Kirkland / UCLA
9:50-10:15 Marissa Schafer / Mayo Clinic
10:15-10:40 Andrea Alimonti / IOR and ETH - Hunting Senescent Cells Through Targeted Immunotherapy
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| 10:40 - 11:10 |
coffee break
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11:10-11:35 Mike Sapieha / Unity Biotechnologies - UBX1325 in Diabetic Eye Disease
11:35-12:00 Daohong Zhou / UT San Antonio - Using PROTAC to Develop Safer and Better BCL-XL/2 Targeting Senolytics for MAFLD/MASH
12:00-12:25 Frederick Beddingfield / Life Sciences - A phase 1 study examining the impact of a novel topical GPX4 modulator and senolytic in inflammatory skin conditions and aging skin
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| 12.25 - 12.55 |
Round table 1: biomarkers and clinical trial design for SenoTherapeutics
Frederick Beddingfield / Rubedo Life Sciences
James Kirkland / UCLA
Marissa Schafer / Mayo Clinic
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| 12.55 - 13.55 |
lunch break
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| 13.55 - 14.20 |
Alessandra Zatti / Chiesi Pharmaceuticals - Navigating Senotherapeutics in chronic lung diseases
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| 14.20 - 14.50 |
“FederChimia - AssoBiotec" Round table 2: Cellular Senescence & Longevity Therapeutics: Are Big Pharma Ready to Bet on Aging Biology as key driver and mechanism of chronic diseases?
Benjamin Yaden / Eli Lilly
Alessandra Zatti / Chiesi Pharmaceutical
Alessandro Lattuada / Otsuka Pharmaceutical Italy
TBD / Novartis
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| 14.50 - 17.20 |
Session 2: Early-Stage Companies
14:50-15:15 Jia Xiei / OneSkin
15:15-15:40 John Lewis / Oisin
15:40-16:05 Robin Mansukhani / Decidous
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| 16:05 - 16:30 |
coffee break
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| 16:30 - 16:55 |
Kevin Slawin, MD / Phoenix SENOLYTIX - p16Ink4a - ATTAC Mouse Model: From Proof of Concept to Senolytic Gene Therapy to Increase Healthy Lifespan
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| 16:55 - 17:20 |
Kevin Slawin, MD / Eos SENOLYTIX - Novel MitoXcel™ Geropeptides Demonstrate Features of Safe and Effective Gerotherapeutics
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| 17:20 - 17:50 |
Round table 3: From Gene Delivery to Decentralized Discovery – Translating Senescence Science into the Next Generation of SenoTherapeutics
Paolo Binetti / VitaDAO
Mac Davis / Minircle
TBD / Healthspan Ventures
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| 17.50 - 18.15 |
Conclusions and final remarks
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Wednesday September 17th
| 08.30 - 09:00 | Registration |
| 09.00 - 09:30 | Opening Remarks and ICSA history (Marco Demaria & Dot Bennett) |
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09:30 - 10:40 |
Session 1 09:30-09:50 Bill Keyes |
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10:40 - 11:20 |
coffee break |
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11:20 - 12:40 |
Session 2 - Viral induced senescence: 11:20-11:40 François Trottein |
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12:40 - 13:10 |
Flash talks/poster teasers selected from abstracts (7 x 3 min) |
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13:10 - 15:00 |
Lunch + Poster Session 1 (even-numbered posters) |
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15:00 - 16:40 |
Session 3 15:00-15:20 Ana O’Loghlen |
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16:40 - 17:40 |
Keynote Speaker: Laura Niedernhofer |
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18:15 - 20:30 |
Welcome Reception (off-site at La Limonaia,, approx. 20 min walking) |
Thursday September 18th
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09:00 - 10:40 |
Session 4 09:00-09:20 Eugenio Barone |
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10:40 - 11:20 |
coffee break |
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11:20 - 12:30 |
Session 5 11:20-11:40 Valery Krizhanovsky |
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12:30 - 13:00 |
Flash talks/poster teasers selected from abstracts (8 x 3 min) |
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13:00 - 15:00 |
Lunch + Poster Session 2 (odd-numbered posters) |
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15:00 - 16:50 |
Session 6 15:00-15:20 Keiko Kono |
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17:00 - 18:00 |
yICSA Event (limited to early career researchers) - Feat. RafaellaDi Micco & Masashi Narita |
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20:00 |
Gala Dinner & Party – Baja Roma |
Friday September 19th
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09:30 - 11:15 |
Session 7 09:30-09:50 Maria Cavinato-Nascimento |
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11:10 - 11:50 |
coffee break |
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11:50 - 12:55 |
General assembly, closure and poster prizes |
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12:55 - 14:10 |
Lunch |
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15:00 - 17:00 |
Optional guided tour of the historic City Center |